Ralph F. Hirschmann Professor of Medicinal and Organic Chemistry
University of Wisconsin-Madison College of Pharmacy and Department of Chemistry
Born December 12, 1942 in Fairmont, Minnesota.
B.S. degree, Chemistry major, University of Minnesota in 1964 (W.E. Noland)
Ph. D. in Organic Chemistry, Cornell University (Ithaca) in 1968 (A. T. Blomquist)
Postdoctoral research: Cornell (V. du Vigneaud ), Stanford (W. S. Johnson)
University of Wisconsin-Madison, Assistant Prof. 1970, Professor 1981
Research:
Synthesis and conformational analysis of cyclic peptides
Design and synthesis of inhibitors of therapeutically important enzymes, especially aspartic proteases including pepsin, renin, cathepsin D, and HIV-I protease
Design and synthesis of peptidemimetics
Understanding of immunosuppressants such as cyclosporin
Design and synthesis of non-immunosuppressive cyclosporin analogs that have anti-viral activities
Synthesis of enzyme inhibitors created by computerized structure-generating programs
Dr. Daniel H. Rich
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