Instructions to Authors
Instructions to Authors |
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Objective
The Proceedings will be published in a uniform manner and as soon as possible after the Symposium has been held. Please adhere strictly to the "Instructions to Authors" and submit your manuscripts prior to the deadline. Authors giving oral presentations will prepare 3-page manuscripts, and selected authors giving poster presentations (including the 12 chosen for the Young Investigators' MiniSymposium) will prepare 2-page manuscripts.
Submission of Manuscripts
Please submit your manuscript on a diskette along with 3 hardcopy printouts at the appropriate desk in the Registration area at the Symposium on or before June 30, 1999. On the disk label write your name, abstract number, title of the paper, type of disk (e.g., Mac, PC) and the word processing program you used (e.g., WordPerfect 6.0, Microsoft Word 98, Word 6.0, etc.). Your computer file should also have a logical name that will enable the editors to readily associate the file with your contribution, e.g. MCGWIRE.Doc is good, MPLS99.Doc is not good (too generic). Click here to download a sample manuscript in a variery of formats
Please check the attached sample manuscript carefully before you start typing your own manuscript. To familiarize yourself with the style, it is also recommended that you consult with either: Proceedings of the 12th American Peptide Symposium: Peptides - Chemistry and Biology, Smith, J.A. and Rivier, J.E. (Eds.) ESCOM, Leiden, The Netherlands, 1992 or Proceedings of the 13th American Peptide Symposium: Peptides - Chemistry, Structure and Biology, Hodges, R.S. and Smith, J.A. (Eds.) ESCOM, Leiden, The Netherlands, 1994. Follow this style strictly as manuscripts that do not follow this style will not be published. We have made every effort with the present instructions and sample manuscript to remove ambiguities and inconsistencies in earlier Symposium instructions.
General Requirements
Preferably, manuscripts should be typed with Microsoft Word 5.1, or higher, e.g., Word 97/98 program on either PC or Macintosh computers with a Times New Roman font. Please use single line spacing ["exact" option for line spacing -- although for pasted in graphics, use "auto" option]. Superscripts and subscripts should be slightly smaller type size, and appear after punctuation marks (see sample). Use a Letter Quality Laser Printer (do not use dot matrix). Each page of your manuscript must fit within a box of 21.5 cm (8.5 in) in height and 15.5 cm (6.1 in) in width. For ease of reference it is recommended that you draw such a box as a guide for the preparation of your manuscript. The sample manuscript with proper dimensions can be downloaded from the website in a number of formats. Use justified margins!
Manuscripts will be reduced to approximately 80% of the original size before printing. Please make sure that all text and numbers in the illustrations remain legible after reduction. (In Microsoft Word, 14 pt in Times New Roman font gives about 11 pt after 80% reduction; this is legible).
Manuscripts include the following sections: Title, Authors names, Affiliations, Introduction, Results and Discussion, Acknowledgments (if appropriate), and References.
Typing the text
| Title | Type single-spaced using a 16 pt bold font face and center on the page. Only the first letter of the first word should be capitalized (except for proper names, abbreviations, etc.). Use line spacing "exact 16 pt." |
Leave two blank lines -12 pt-
| Author(s) | Type single-spaced using a 14 pt bold font face and center on the page. Please use superscript numbers (i.e., 1,2,3) after each surname when there are multiple authors and multiple affiliations. For multiple authors, use commas after each author and the word "and" in front of the last author. A comma is not used when there are only two authors. Whenever possible, avoid splitting a name between two lines. Use line spacing "exact 14 pt." |
No blank line
| Affiliation(s): | Type single-spaced, in upper and lower case using a 11 pt italics font face and center on the page. Please include city, province/state (use abbreviations for USA states), postal/zip code, and country. Please use superscript numbers (i.e., 1,2,3) before each affiliation where there are multiple authors and multiple affiliations. Use semi-colon to separate different institutions, and use the word "and" in front of the last affiliation. Use line spacing "exact 11 pt." |
Leave one blank line -12 pt-
| Introduction | Type the word "Introduction" using a 12 pt bold font face, flush with left margin. |
Leave one blank line -12 pt-
| Introduction (text) | Type the text of the introduction using a 12 pt font face. Do not indent the first word. The first words of subsequent paragraphs should be indented. Reference to figures and tables should be put in parentheses e.g., (Fig. 1), (Table 2). Literature references should be numbered consecutively and the numbers be put in square brackets e.g., [1]. Use line spacing "exact 12 pt," which results in approximately 6 text lines per inch. |
Leave one blank line -12 pt-
| Results and Discussion: | Type the words "Results and Discussion" in 12 pt bold font face, flush with the left margin. |
Leave one blank line -12 pt-
| Results and Discussion (text): | Same as Introduction (text). |
Leave one blank line -12 pt-
| Acknowledgments: | Type the word "Acknowledgments" using a 12 pt bold font face, flush with left margin. |
Leave one blank line -12 pt-
| Acknowledgments: | Same as Introduction (text). |
Leave one blank line -12 pt-
| References: | Type the word "References" using a 12 pt bold font face, flush with left margin. |
Leave one blank line -12 pt-
| References (text): | Type the reference list using a 11 pt font face. Please check the "Reference Style" section of these Instructions carefully as well as the sample article provided. After the reference number and a period, type in two spaces. If the reference goes over one line, use a hanging indent of 0.5 cm for subsequent lines . |
Tables
Tables should be typed using an 11 pt font face and be numbered with Arabic numerals. Captions to tables should precede the table. Captions and the word "Table" and table number should be typed using an 11 pt italics font face. Please check the table in the sample article carefully.
Tables should be placed either at the top or at the bottom of a page. Leave one 12 pt blank line between the text and the caption of a table. Leave one 11 pt blank line between the caption and the table. Tables should be inserted directly into the manuscript.
Illustrations
Please supply 2 original high quality black and white glossy prints of each illustration (line drawings, b/w photographs) and, if possible, also as EPS files on the diskette with your manuscript. Photocopies are not acceptable. Extremely small lettering should be avoided as illustrations are often reduced in size. All illustrations should be marked on the back with the name of the author and abstract number. On the back of all illustrations the top should be indicated. Leave sufficient space open in your manuscript for the insertion of illustrations. Alternatively, authors may insert illustrations directly into the manuscript. Please supply two prints of each illustration even if you insert the illustration directly into the manuscript.
There should be one blank line using an 11 pt font face between the legend of the figure and the text. Legends should be typed using an 11 pt italics font face. The word "Figure" should be abbreviated to "Fig." both in the legend and in the text, e.g., Fig. 1.
Formulas and Equations
Superscripts and subscripts should be clear. Exponents and mathematical fractions should be arranged on a single line. Chemical structures are considered to be "Illustrations" and should be submitted as either a copy suitable for photographic reproduction or inserted directly into the manuscript.
Nomenclature and Abbreviations
Nomenclature should be consistent and be conforming to therecommendations of the International Union of Pure and Applied Chemistry, International Union of Biochemistry, and other appropriate bodies. Use standard abbreviations, e.g. HPLC, NMR, etc. A list of commonly used abbreviations is enclosed. Non-commonly used abbreviations should be provided, in parentheses, when it is first used in the text. The position of amino acids should be superscripted following the three letter amino acid code, e.g. Asp100. Use 10 pt capitals to indicate ‘L’ and ‘ D’ amino acids. Compound numbers should be in bold Arabic numerals.
Reference Style
| Journals | Barbar, E., Barany, G., and Woodward, C., Folding and Design 1 (1995) 65. |
| Books | |
Edited Volume |
Annis, I. and Barany, G., In Tam, J.P. and Kaumaya, P.T.P. (Eds.) Peptides: Frontiers of Peptide Science (Proceedings of the 15th American Peptide Symposium), Kluwer, Dordrecht, 1999, p. 343. |
Monograph |
Lloyd-Williams, P., Albericio, F., and Giralt, E., Chemical Approaches to the Synthesis of Peptides and Proteins. CRC Press, Boca Raton, 1997. |
When there are only two authors, there is no comma before the word "and;" otherwise, use commas throughout as shown in the examples. Refer to unpublished material in the text only, e.g., (C.S. Andrew, unpublished), e.g., (D. Wilman, personal communication).
Abbreviations
| µ | hydrophobic moment |
| [q] | mean residue ellipticity |
| Abc | 4’-aminomethyl-2,2’-bipyridine-4-carboxylic acid |
| Abh | azabicyclo[2.2.1]heptane-2-carboxylic acid |
| Abl | Abelson kinase |
| Abu | a-amino-n-butyric acid |
| Abz | 2-amino-benzoic acid;2-aminobenzoyl |
| AC | adenylyl cyclase |
| Ac | acetyl; acyl |
| Aca | adamantanecarboxyl- |
| Acc | 1-aminocyclopropane-1-carboxylic acid |
| Acm | acetamidomethyl |
| AEDI | aminoethyldithio-2-isobutyric acid |
| Ahp | 2-amino-heptanoic acid |
| D6Ahp | 6-dehydro-2-amino-heptanoic acid |
| Ahx | 6-aminohexanoic acid |
| Aib | a-aminoisobutyric acid |
| AII | angiotensin II |
| Al | allyl |
| Alloc | allyloxycarbonyl |
| AM | alveolar macrophage |
| AMBER | assisted model building and energy refinement |
| AMC | aminomethylcoumaride |
| AMCA | 7-amino-4-methylcoumarin-3-acetic acid |
| Amn | 8-(aminomethyl)naphth-2-oic acid |
| AMPA | o-aminomethylphenylacetic acid |
| APB | (4-amino)phenylazobenzoic acid |
| APC | antigen presenting cell |
| Apn | 5-aminopentanoic acid |
| Arg-al | argininal |
| Arg-ol | argininol |
| ATP | adenosine triphosphate |
| AUC | area under the curve |
| AVP | vasopressin |
| BAL | backbone amide linker |
| BApG | N,N-bis(3-aminopropyl)-glycine |
| BBB | blood brain barrier |
| BK | bradykinin |
| BMAP | bovine myeloid antimicrobial peptide |
| BME | b-mercaptoethanol |
| Boc | tert-butyloxycarbonyl |
| Boc-ON | 2-tert-butyloxy-carbonylamino-2-phenylacetonitrile |
| Boc2O | di-tert-butyl dicarbonate |
| BOP | (benzotriazol-1-yloxy)-tris(dimethylamino)phosphoniumhexafluorophosphate |
| Bpa | p-benzoylphenylalanine |
| BPTI | bovine pancreatic trypsin inhibitor |
| Bpy | 2,2’-bipyridine |
| Bzl | benzyl |
| CAMM | computer assisted molecular modeling |
| Cbz | carbobenzoxy;benzyloxycarbonyl |
| CCk | cholecystokinin |
| CD | circular dichroism |
| b-CD | b-cyclodextrin |
| CED3 | Cenorhabditis elegans cell-death protein |
| CF | 5(6)-carboxyfluorescein |
| CFU | colony forming units |
| Cha | cyclohexylalanine |
| Chg | a-cyclohexylglycine |
| Clt | 2-chlorotrityl |
| Cl-Z | 2-chlorobenzyloxycarbonyl |
| Cpg | a-cyclopentylglycine |
| CRF | corticotropin releasing Factor |
| CTL | cytotoxic T-lymphocyte |
| d.e. | diastereomeric excess |
| Da | Dalton |
| DB[DMAP] | 2,6-di-tert-butyl-4-(dimethylamino)pyridine |
| DBU | 1,8-diazabicyclo[5.4.0]-undec-7-ene |
| DCC | dicyclohexylcarbodimide |
| DCM | dichloromethane |
| Dde | 1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl |
| Ddz | 2-(3,5-dimethoxyphenyl)-propyl[2]oxycarbonyl |
| DIEA | N,N-diisopropylethylamine |
| DIPCDI | N,N’-diisopropylcarbodiimide |
| DMAP | 4-(dimethylamino)pyridine |
| DMER-Plot | difference minimum energy Ramachandran plot |
| DMF | N,N-dimethylformamide |
| DMSO | dimethyl sulfoxide |
| Dnp | 2,4-dinitrophenyl |
| DTT | dithiothreitol |
| EAE | experimental allergic encephalomyelitis |
| EBP | erytropoietin binding protein |
| EBV | Epstein-Barr-virus |
| ED50 | median effective dose |
| EDT | 1,2-ethanedithiol |
| EDTA | ethylenediamine-tetraacetic acid |
| EGF | epidermal growth factor |
| EGFR | EGF receptor |
| EGS | ethylene glycol bis-succinyl- |
| ELISA | enzyme linked immunosorbance assay |
| EMP | erythropoietin mimetic protein |
| EPO | erythropoietin |
| ES-MS | electrospray mass spectrometry |
| ESR | electron spin resonance |
| ESTs | expressed sequence tags |
| ET-1 | endothelin-1 |
| ET R | endothelin-A receptor |
| F2Pmp | difluorophosphonomethyl phenylalanine |
| FAB-MS | fast atom bombardment mass spectrometry |
| FceRI | IgE-receptor |
| FceRIa | IgE-receptor-a-subunit |
| FITC | fluorescein isothiocyanate |
| fMLP | formyl-Met-Leu-Phe |
| Fmoc | 9-fluorenylmethoxycarbonyl |
| Fmoc-Cl | 9-fluorenylmethoxy chloroformate |
| FTIR | Fourier transform infrared |
| GalR | galanin receptor |
| GdnHCl | guanidinium hydrochloride |
| GFC | gel filtration chromatography |
| GlcNAc | N-acetylgalactosamine |
| GPCR | G-protein-coupled receptor |
| GpIIb/IIIa | glycoprotein IIb/IIIa |
| Grb2 | growth factor receptor-bound protein 2 |
| GRF | growth hormone releasing factor |
| GS | gramicidin S |
| GSH | reduced glutathione |
| GSSG | oxidized glutathione |
| HATU | N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate N-oxide |
| HBTU | O-benzotriazolyl-N,N,N’,N’-tetramethyluronium hexafluorophosphate |
| HBV | hepatitis B virus |
| HCV | hepatitis C virus |
| HDV | hepatitis delta virus |
| HFIP | hexafluoroisopropanol |
| HG | human gastrin |
| HIV | human immunodeficiency virus |
| HLA | human leukocyte antigen |
| HMPA | p-hydroxymethylphenoxyacetic acid |
| HMPA | hexamethylphosphoramide |
| HMPB | 4-(4-hydroxymethyl-3-methoxyphenoxy)-butyric acid |
|
1 H-NMR |
proton nuclear magnetic resonance |
| HOAt | 1-hydroxy-7-azabenzotriazole |
| HOBt | 1-hydroxybenzotriazole |
| HPLC | high performance liquid chromatography |
| Hpp | 3-(4-hydroxyphenyl)proline |
| HPV | human papilloma virus |
| HSBOtU | (2-mercaptobenzoxazol-2-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate |
| HSBtU | 2-(1-mercaptobenzoxazol-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate |
| HSF | hematopoietic synergistic factor |
| HSNPtU | 2-(1-mercapto-4-nitrophenyl-1-y1)-1,1,3,3-tetramethyluroniumhexafluorophosphate |
| HSDNPtU | 2-(1-mercapto-2,4-dinitrophenyl-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate |
| HTLV | human T cell leukemia virus |
| i.v. | intravenous |
| IAPP | ilet amyloid polypeptide |
| IBoc | isobutyloxycarbonyl |
| IC50 | 50% inhibition concentration |
| ICE | interleukin-1b converting enzyme |
| IFN | interferon |
| IL-1b | interleukin-1b |
| IP3 | inositol trisphosphate |
| ITC | isothermal titration calorimetry |
| LAH | lithium aluminum hydride |
| LDL | low density lipoprotein |
| LHR | lutropin receptor |
| LPS | lipopolysaccharide |
| LUV | large unilamelar vesicle |
| mAb | monoclonal antibody |
| MAdCAM-1 | mucosal addressin cell adhesion molecule-1 |
| MALDI | matrix-assisted laser desorption/ionization |
| MALDI-TOF | MALDI time-of-MSflight mass spectrometry |
| MAP | multiple antigenic peptide |
| Mbc | 4’-methyl-2,2’-bipyridine-4-carboxylic acid |
| MBHA | p-methylbenzhydrylamine |
| MBP | myelin basic protein |
| MCR | melanocortin receptor |
| MD | molecular dynamics |
| MDP | muramyl dipeptide |
| Me | methyl |
| MeCN | acetonitrile |
| MeOBzl | p-methoxybenzyl |
| MeOH | methanol |
| MER-Plot | minimum energy Ramachandran plot |
| MHC | major histocompatibility complex |
| MIC | minimum inhibitory concentration |
| MIF | macrophage migration inhibitory factor |
| MMP | matrix metalloproteinase |
| Mmt | 4-methoxytrityl |
| MS | mass spectrometry |
| MSH | melanocyte stimulating hormone melanotropin |
| Mtr | 2,3,6-trimethyl-4-methoxybenzenesulfonyl |
| Mtt | 4-methyltrityl |
| NADPH | nicotinamide adeninedinucleotide phosphate,reduced form |
| Nip | nipecotic acid |
| NIR-FT | near-infrared, Fourier-transform |
| NK-1 | neurokinin-1 receptor (substance P receptor) |
| NKA | neurokinin A |
| NKB | neurokinin B |
| NKR cells | normal rat kidney cells |
| NMePhe | N-methyl phenylalanine |
| NMM | N-methylmorpholine |
| NMP | N-methylpyrrolidinone |
| NMR | nuclear magnetic resonance |
| NO | nitric oxide |
| nOct | n-octanoyl |
| NOE | nuclear overhauser effect |
| NOESY | nuclear overhauser enhanced spectroscopy |
| NPY | neuropeptide Y |
| Npys | 5-nitro-2-pyridinesulfenyl |
| Ntc | nortropane-3-carboxylic acid |
| O | defined sequence position in peptide libraries |
| O/X10 | the complete set of 220 sublibraries |
| OChx | cyclohexyl ester |
| OHA | octahydroacridine |
| OPT | oligopeptide transport |
| Orn | ornithine |
| OVX | ovariectomy |
| PAL | peptide amide linker, 5-(4-Fmoc-aminomethyl-3,5-dimethoxyphenoxy)valeric acid |
| PBMC | peripheral blood mononuclear cells |
| PBS | phosphate-buffered saline |
| PC | phosphatidylcholine |
| PCR | polymerase chain reaction |
| Pd/C | palladium on carbon |
| PDI | protein disulfide isomerase |
| PEG | polyethylene glycol |
| PEG-PS | polyethylene glycol-polystyrene copolymer |
| Pen | penicillamine |
| Pfp | pentafluorophenyl ester |
| —Phe | a,b-dehydrophenylalanine |
| DPhe | cyclopropylphenylalanine |
| PI | phosphatidylinositol |
| PLC | phospholipase C |
| PLN | phospholamban |
| PLP | proteolipid protein |
| PM | plasma membranes |
| Pmc | 2,2,5,7,8-pentamethylchroman-6-sulfonyl |
| PMD | Pelizaeus Merzbacher disease |
| pNA | p-nitroaniline |
| PPCE | post-proline cleaving enzyme |
| PS | polystyrene |
| PSD/CID | post source decay/collision-induced dissociation |
| PS-SCL | positional scanning SCL |
| PTH | parathyroid hormone |
| PTHrP | parathyroid hormone related protein |
| PTK | protein tyrosine kinase |
| PTP | protein tyrosine phosphatase |
| PTR | peptide transport |
| pTyr | phosphotyrosine |
| PyAOP | (7-azabenzotriazol-1-yloxy)-tris(pyrrolidino)phosphonium hexafluorophosphate |
| PyBOP | (benzotriazol-1-yloxy)-tris(pyrrolidino)phosphonium hexafluorophosphate |
| QSAR | quantitative structure-activity relationships |
| RGD | Arg-Gly-Asp |
| RMSD | root mean square deviation |
| RNA | ribonucleic acid |
| RP | reversed-phase |
| RP-HPLC | reversed-phase HPLC |
| RuCl2(dmso)4 | dichlorotetrakis(dimethyl sulfoxide) ruthenium(II) |
| SAPS | sequence assisted peptide synthesis |
| SAR | structure activity relationships |
| SCLs | synthetic combinatorial libraries |
| SD | standard deviation |
| SH2 | src homology domain 2 |
| SH3 | src homology domain 3 |
| SIOM | 7-spiroindoyloxymorphone |
| SP | substance P |
| SPPS | solid-phase peptide synthesis |
| SPR | surface plasmon resonance |
| SUV | small unilamellar vesicle |
| SynJ | synthetic J protein |
| TASP | template-assembled synthetic protein(s) |
| TBDMS | tert-butyldimethylsilyl |
| tBu | tert-butyl |
| TCEP | tris(carboxyethyl)phosphine |
| TEA | triethylamine |
| TEMP | 2,3,5,6-tetramethylpyridine |
| TFA | trifluoroacetic acid |
| TFE | trifluoroethanol |
| TFFH | tetramethylfluoroformamidiniumhexafluorophosphate |
| TFMSA | trifluoromethanesulfonic acid |
| TGFa | transforming growth factor alpha |
| THF | tetrahydrofuran |
| Thi | b-(2-thienyl)-alanine |
| THP | triple-helical peptide |
| Tic | 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid |
| TLC | thin layer chromatography |
| TMH | transmembrane helix |
| Tmob | 2,4,6-trimethoxybenzyl |
| TMP | 2,4,6-trimethylpyridine |
| TMS-Cl | trimethylsilyl chloride |
| TMT | b-methyl-2,6’-dimethyltyrosine |
| TOAC | 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid |
| TOCSY | total correlation spectroscopy |
| Tos | p-toluenesulfonyl |
| TPTU | 2-(2-oxo-1(2H)-pyridyl)-1,1,3,3-tetramethyluroniumtetrafluorophosphate;2-(2-pyridon-1-yl)-1,1,3,3-tetramethyluronium fluoroborate |
| TRH | thyrotropin-releasinghormone |
| Tris | tris(hydroxymethyl) aminomethane |
| Trt | trityl |
| TsOH | p-toluenesulfonic acid |
| Tyr(NO2) | 3-nitrotyrosine |
| X | randomized sequenceposition in peptide libraries |
| XAL | 5-(9-aminoxanthen-2-oxy)valeric acid |
| Xan | 9H-xanthen-9-yl |
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Download the sample manuscript in any of the following formats. The sample is set with the proper margins and has proper formats. Instructions for manuscript submission are given above. The editors will require both hardcopy and electronic versions.
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