Biological Chemistry of Organotin Compounds: Interactions and Dealkylation by Dithiols

Buck-Koehntop, B. A.; Porcelli, F.; Lewin, J. L.; Cramer, C. J.; Veglia, G.
J. Organomet. Chem. 2006, 691, 1748.

In this paper, we review our past and current efforts toward the elucidation of the biological chemistry of organotin compounds. In particular, we cover two prominent aspects of organotin compounds: their reactivity toward biological dithiols, and their degradation (or metabolization) mechanism using a combination of experimental and computational techniques.

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