Overview

Analytical Chemistry

Immunology

Toxicology


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The Haynes group focuses on applications of analytical chemistry in the fields of immunology and toxicology, with much expertise in the area of single cell analysis.

One major area of interest is nanotoxicology - an emerging field investigating the biological and ecological impacts of engineered nanomaterials.

Another major focus in the group is on studying fundamental properties of cells involved in inflammation. In fact, the Haynes group has performed the first ever real-time single blood platelet measurements, examining the chemical messenger molecules that platelets secrete upon stimulation.

While most of the Haynes lab research employs electrochemical and spectroscopic techniques, the group is always exploring new and exciting technologies to answer pressing bioanalytical questions.

News

11.21.2016

Congratulations to Natalie and Peter on the acceptance of their collaborative CSN research highlight, titled "Speciation and transformations of silver released from Ag NPs in three species," in the journal Environmental Science: Nano.

11.14.2016

The Haynes group happily welcomes three new graduate students to the group: Peter Clement, Jiayi He, and Becky Rodriguez. You can learn more about them on our people page.

11.03.2016

Bo's blog post about appreciating parallels between nano-art and the macro-scale natural world is featured on the Sustainable Nano blog.

10.28.2016

Natalie's blog post about how nanoscale features on ivy let it climb brick walls is featured on the Sustainable Nano blog.

10.22.2016

Autumn's collaborative work exploring the toxicity of nanoscale titania to S. oneidensis is accepted for publication in Chemosphere.

10.19.2016

Christy is featured in The Analytical Scientist's annual "Power List".

10.10.2016

Congratulations to alumna Audrey Meyer on the publication of her work in collaboration with the Arriaga group to do untargeted MS analysis of mast cell-secreted species.

10.04.2016

Christy's blog entry "Let's Talk about Responsible Science Communication" is featured on the Sustainable Nano blog and picked up by Science Seeker.

09.27.2016

Congratulations to Zhe on winning 1st place at the Institute for Engineering in Medicine postdoc poster session!

09.21.2016

Congratulations to Sunipa on winning a FACSS student poster award at SciX 2016!

09.18.2016

Congratulations to Victoria on winning a Journal of Physical Chemistry poster award at the Van Duyne symposium!

09.15.2016

Haynes group alumnus, Dr. Audrey Meyer, accepts a new position as a Senior Process Engineer at Boston Scientific (back in the Twin Cities!). We wish her well in this new role!

09.06.2016

A new semester is underway, and the Haynes group meeting schedule is now available. New first year graduate students are welcome to join us to learn more about the group.

08.31.2016

Congratulations to Zhe on the acceptance of her collaborative work with the Hogan and Bischof groups, titled "Ion Mobility based Quantification of Surface Coating Dependent Binding of Serum Albumin to Superparamagnetic Iron Oxide Nanoparticles," in the journal ACS Applied Materials and Interfaces.

08.29.2016

Congratulations to Ben, Sarah, and Audrey (all graduated!) on the acceptance of their collaborative work titled "Analysis of Neuropeptide-Induced Mast Cell Degranulation and Characterization of Signaling Modulation in Response To IgE Conditioning," in the journal ACS Chemical Biology.

08.26.2016

Haynes group alumnus, Dr. Yu-Shen Lin, accepts a new position as Senior Research Chemist at Ferrotec Corporation in New Hampshire. We wish him well in his new role!

08.20 - 08.24.2016

Christy attends the Fall 2016 National ACS Meeting in Philadelphia and gives 4 invited talks: one on work determining the role of lipopolysaccharides in regulating nanoparticle/bacteria interactions, one on biomedical applications of mesoporous silica-coated iron oxide nanoparticles, one on single cell platelet measurements, and one on toxicity assessment of nanoscale battery materials. It was an exhausting but exciting conference!

08.18.2016

Congratulations to Katie on the acceptance of her collaborative work with the Hogan and Bischof groups, titled "Quantifying Intra- and Extracellular Aggregation of Iron Oxide Nanoparticles and its Influence on Specific Absorption Rate," in the journal Nanoscale.

08.15.2016

Christy officially joins the the "Nanostructural Materials and Processes Program" within the University of Minnesota's IPrime program. This new affiliation will help promote collaboration between the Haynes research group and industrial scientists and engineers.

08.14-08.18.2016.2016

Christy and Joe attend the ICEENN meeting in Golden, CO where Christy delivers a keynote talk and Joe presents a poster. They also get to spend time with CSN collaborators Prof. Rebecca Klaper, Prof. Howard Fairbrother, Arielle Mensch, Emily Caudill, Liz Laudadio, Margy Roberts, and Jared Bozich.

08.11.2016

Congratulations to Autumn and Natalie on the acceptance of their collaborative CSN research highlight, titled "Unveiling the mechanisms underlying nanoparticle-induced ROS generation and oxidative stress," in the journal Environmental Science: Nano.

08.10.2016

Congratulations to Solaire, Autumn, and Kayeong on the acceptance of their perspective article "Super-Resolution Imaging for Monitoring Cyotskeleton Dynamics" in Analyst.

08.08.2016

Haynes group alumnus, Dr. Secil Koseoglu, accepts a new position at Takeda Pharmaceuticals in Boston. We wish her well in this new role!

08.04.2016

The group had our annual pie bake-off to complment our end-of-summer undergraduate symposium. Both the talks and the pie were fantastic!

08.03.2016

Congratulations to Hattie for co-leading collaborative work with the Garwood and Bischof groups titled "Quantification and Biodistribution of Iron Oxide Nanoparticles in the Primary Clearance Organs of Mice using T1 Contrast for Heating" that was just accepted for publication in Magnetic Resonance in Medicine.

08.03.2016

Xiaojie Wu successfully defends his PhD thesis entitled "Development of Biomimetic Microfluidic Platforms for Cellular Interaction Studies."

08.01.2016

The Haynes group along with selected members of the Carlson, Frontiera, and Feng labs spend the afternoon at W. 7th Community Center doing demonstrations and hands-on activities with 70 children. This 11th annual event was organized by Natalie, and everyone had a great time.

07.06.2016

Congratulations to Amani on being chosen as a trainee for the Chemical Biology Interface Training Grant.

07.04.2016

Congratulations to Zhe for leading collaborative work on SERS sensing in core-shell nanoparticles; her paper was just accepted for publication in Analyst.

06.21.2016

Congratulations to Natalie on being chosen as a trainee for the University of Minnesota Biotechnology Training Grant.

06.14.2016

Welcome to Peter Clement, an incoming Chemistry graduate student, who will be spending the summer in the Haynes lab working with mentor Natalie Hudson-Smith.

06.10.2016

Collaborative work led by Tony titled "Surface-Enhanced Raman Spectroscopy Detection of Ricin B Chain in Human Blood" is accepted for publication in Journal of Physical Chemistry C to be part of the "Richard P. Van Duyne Festschrift" special issue.

06.6.2016

Welcome to Anna Krieger, a Department of Chemistry Lando REU, who will be spending the summer in the Haynes lab working with mentor Kang Xiong-Hang.

06.01-06.02.2016

Victoria and Christy give invited talks while Zhe, Joe, and Sunipa present posters at IPrime 2016.

05.31.2016

Welcome to Susan Pham, a Center for Sustainable Nanotechnology REU, who will be spending the summer in the Haynes lab working with mentor Bo Zhi.

05.26.2016

Collaborative work led by Victoria titled "SERS Detection of Ricin B-Chain via N-Acetyl-Galactosamine Glycopolymers" is accepted for publication in ACS Sensors.

05.10.2016

Christy gives an invited seminar at The Ohio State University.

05.05.2016

Nathan Klein successfully defends his undergraduate honors thesis entitled "Analytical Studies of Inorganic Nanoparticle Applications: Imaging in Complex Biological Matrices and Heat-mediated Cargo Release."

05.03.2016

Ian Gunsolus successfully defends his PhD thesis entitled "Engineered Nanomaterial Interactions with Bacterial Cells."

04.26.2016

Kyle Johnson is chosen as a winner of the Thomas DuBruil Undergraduate Research Award for 2016. This award is made to a junior who has demonstrated outstanding achievement in undergraduate research in chemistry at the University of Minnesota.

04.21.2016

Sarah Gruba successfully defends her PhD thesis entitled "Exploration of Platelet and Mast Cell Communication: A Study of Membrane Lipids, Asthma, and Inflammation."

04.07.2016

Christy gives an invited seminar in the Chemistry Department at University of Arizona.

04.02.2016

Undergraduate researcher Kyle Johnson has been awarded a Heisig-Gleysteen Fellowship to support full-time summer research in the Haynes lab- congratulations to Kyle!

03.29.2016

Former undergraduate researcher Matt Styles, now in Helen Blackwell's research group at UW - Madison, is awarded an honorable mention in the 2016 National Science Foundation Graduate Research Fellowship competition.

03.29.2016

Undergraduate researcher Nathan Klein is awarded a 2016 National Science Foundation Graduate Research Fellowship to support his future graduate work - congratulations to Nathan!

03.18.2016

Collaborative work led by Katie titled "Predictable Heating and Positive MRI Contrast from a Mesoporous Silica-Coated Iron Oxide Nanoparticle" is accepted for publication in Molecular Pharmaceutics.

03.03.2016

Christy gives an invited seminar titled "Leveraging Analytical Methods to Explore Platelet Biology" in the University of Minnesota Department of Integrative Biology and Physiology.

02.04.2016

Ian, Christy, and collaborators are featured in local news segments on FOX9 and KARE11 discussing recent work on NMC interaction with bacteria. The work is also covered in the Minnesota Daily, Science Daily, Watts Up With That?, and Green Car Congress.

01.29.2016

Hyunho passes his PhD candidacy exam - congratulations!

01.28.2016

Solaire Finkenstaedt-Quinn successfully defends her PhD thesis entitled "A Study on the Regulation Mechanisms of Platelet Activation."

01.22.2016

A manuscript describing work done jointly by Ian and CSN collaborator Mimi Hang, titled "Impact of Nanoscale Lithium Nickel Manganese Cobalt Oxide (NMC) on the Bacterium Shewanella oneidensis MR-1" is accepted for publication in Chemistry of Materials.

01.21.2016

Bo passes his PhD candidacy exam - congratulations!

01.06.2016

Undergraduate researcher, Eileen McIntire, joins the Haynes research group to work with mentor Sunipa Pramanik to assess the bacterial toxicity of silicon nanocrystals.

01.01.2016

Christy joins the board of OXIDE, the "Open Chemical Collaborative in Diversity Equity".

12.31.2015

A manuscript describing work done by Solaire and Sarah, titled "Variations in Fusion Pore Formation in Cholesterol-Treated Platelets" is accepted for publication in Biophysical Journal.

12.29.2015

A manuscript describing work done by Tony in collaboration with the Penn lab, titled "Quantifying Gold Nanoparticle Concentration in a Dietary Supplement Using Smartphone Colorimetry and Google Applications" is accepted for publication in the Journal of Chemical Education.

12.16.2015

Christy gives an invited talk at Pacifichem in Honolulu, Hawaii.

12.01.2015

Christy is featured on the Analytical Chemistry podcast discussing the group's recent feature article about monitoring magnetic nanoparticles in biological matrices.

11.13.2015

Christy's blog post is featured on the sustainable-nano.com website.

11.12.2015

A review article written by Ian, titled "Analytical Aspects of Nanotoxicology," is accepted for publication in Analytical Chemistry.

11.09.2015

Christy gives a talk at the 2015 Sustainable Nanotechnology Organization meeting in Portland, Oregon.

11.04.2015

Kadir's blog post is featured on the sustainable-nano.com website.

11.02.2015

Collaborative Center for Sustainable Nanotechnology work led by Dr. Vivian Feng is identified as one of the 25 most downloaded Chemical Science articles between July-September 2015.

11.01.2015

Christy co-edits a joint "virtual issue" between Chemical Research in Toxiciology, ACS Nano, and Nano Lett on the topic of Nanoparticle Toxicology.

10.29.2015

Autumn's blog post is featured on the sustainable-nano.com website.

10.01.2015

Christy gives a talk at SciX 2015 in Providence, RI.

09.28.2015

Congratulations to Dr. Hattie Ring for winning 1st place in the post doc division of the poster competition at the Instintute for Engineering in Medicine annual conference.

09.24.2015

Dona-Carla Forester joins the group as a new undergraduate researcher - she will be working with Autumn doing nanotox research.

09.23.2015

Longtime undergraduate researcher, Kadir, departs for a 3 month research exchange in Germany.

09.18.2015

Christy gives an invited seminar at Hope College in Holland, MI.

09.11.2015

A feature article written by Katie, Hattie, Hyunho, and Nathan, titled "Characterization of Magnetic Nanoparticles in Biological Matrices," is accepted for publication in Analytical Chemistry.

09.10.2015

Collaborative work with the Massari lab exploring molecular confinement in mesoporous silica is accepted for publication in Journal of Physical Chemistry C.

09.01.2015

The Center for Sustainable Nanotechnology is funded as a phase 2 "Center for Chemical Innovation." With this accomplishment, the collaborative team will have the opportunity to work together for the next 10 years. Christy has accepted the official position of Associate Director for the center.

08.27.2015

The Haynes group makes their annual pilgrimage to the Minnesota State Fair.

08.25.2015

Katie Hurley successfully defends her PhD thesis entitled "The Power of Rust and Sand at the Nanoscale: Iron Oxide and Mesoporous Silica Nanoparticles for Biomedical Applications."

08.17.2015

The phase 1 women faculty of the Center for Sustainable Nanotechnology, including Christy, are recognized among the top 100 Inspiring Women in STEM by "Insight into Diversity" magazine.

08.16 - 08.20.2015

Victoria, Solaire, and Christy attend and present the group's work at the ACS National Meeting in Boston, MA.

08.02.2015

Autumn and Ian's collaborative work with the Klaper and Murphy groups throught the CSN is accepted for publication in ES:Nano.

07.31.2015

Congratulations to Solaire on winning a travel award from the MN Section of the American Chemical Society! This award will support her attendance and presentation at the Boston ACS meeting in August 2015.

07.31.2015

As Prof. Vivian Feng finishes her year sabbatical in the Haynes lab, she took the Haynes lab out for celebratory ice cream at Izzy's. We will miss seeing her everyday but look forward to continued collaboration.

07.30.2015

Ian and Kadir's collaborative work with the Buhlmann group is accepted for publication in Science of the Total Environment.

07.26.2015

The Haynes group went canoeing on Medicine Lake on this beatiful summer day.

07.24.2015

Ian's work on the critical role of lipopolysaccharides in nanoparticle/bacteria interactions, done with collaborators in the Center for Sustainable Nanotechnology, is accepted for publication in Environmental Science & Technology.

07.10.2015

An editorial on the topic of gender-based implicit bias that Christy co-wrote with Jonathan Sweedler is published in Analytical Chemistry.

07.01.2015

Christy becomes the Department of Chemistry's vice chair.

06.29.2015

Sarah Schoeller, a MRSEC RET, joins the Haynes group for a summer research experience.

06.21 - 06.26.2015

Autumn, Ian, and Christy spend an intellectually stimulating week at the "Environmental Nanotechnology" GRC in Vermont.

06.15.2015

An ACS SEED program high school student, Ka Lia Xiong, joins the Haynes group for the summer to work with Joe.

06.15.2015

An incoming UMN graduate student, Amani Lee, joins the Haynes group for the summer to work on a collaborative project with the Pomerantz group.

06.05.2015

Xiaojie and Molly's microfluidic study of neutrophil transendothelial migration is accepted for publication in Analyst.

06.05.2015

Ian and Kadir's collaborative work with Maral in the Buhlmann lab is accepted for publication in Environmental Science & Technology.

06.02.2015

Sara, Autumn, and Victoria all give talks at the UMN 3rd year graduate symposium.

06.01.2015

Three undergraduates join the lab for the summer: Nathan (from Macalester, working with Autumn), Jake (from Tulane, working with Sunipa), and Emily (from Ripon, working with Xiaojie). More to come soon...

05.29.2015

A massively collaborative Center for Sustainable Nanotechnology "outlook" on nanoparticle sustainability is accepted for publication in ACS Central Science.

05.26.2015

Christy gives an invited seminar in 3M's "Tech Forum".

05.15.2015

Christy is awarded the 2015 Sara Evans Faculty Woman Scholar/Leader Award sponsored by the University of Minnesota Office for Faulty and Academic Affairs and the Women’s Center.

05.08.2015

Ben, Audrey, and Sarah's work on airway smooth muscle-related mast cell degranulation is accepted for publication in Biochimica et Biophysica Acta - General Subjects.

05.05.2015

Katie's blog post is featured on the sustainable-nano.com website.

05.01.2015

Nathan is chosen as our department's recipient of the 2015 David A. and Merece H. Johnson Scholarship for outstanding achievement in undergraduate research as well as overall scholastic excellence.

04.28.2015

Undergraduate researcher Nathan Klein is featured in the Star Tribune.

04.28.2015

Ian is chosen to receive a 2015-2016 University of Minnesota Doctoral Dissertation Fellowship.

04.21.2015

Katie's blog post is featured on the sustainable-nano.com website.

04.21.2015

Christy gives an invited talk at the ASME 4th Annual "Nanoengineering for Biology and Medicine" conference.

04.20.2015

After being nominated by Haynes group graduate students, Christy is is chosen for the "2015 Advising and Mentoring Award" given by the UMN Graduate and Professional Student Assembly.

04.15.2015

Sam, Katie, and Ashish's work on creating large pore volume silica nanoparticles is accepted for publication in Chemistry of Materials.

04.15.2015

Christy gives an invited talk at the University of Minnesota "Design of Medical Devices" conference.

04.14.2015

Sarah, Secil, Audrey, Ben, and Melissa's work on how platelets differ across species is accepted for publication in Biochimica et Biophysica Acta - Biomembranes.

04.10.2015

Christy gives an invited seminar at Gustavus Adolphus College in St. Peter, MN.

04.06.2015

Antonio Campos successfully defends his PhD thesis entitled "Surface-enhanced Raman Spectroscopy of Analytes in Blood".

04.06.2015

Haynes group undergraduates Adam, Kyle, and Kadir are all awarded UROP funding to support their research.

04.03.2015

Christy gives an invited seminar at the University of Pittsburgh.

04.03.2015

Haynes group undergraduate Nathan Klein is awarded a prestigious Goldwater Fellowship.

04.02.2015

Nathan, Katie, and Vivian's work developing dark field TEM as a technique to visualize nanoparticles within complex biological matrices is accepted for publication in Analytical Chemsistry.

04.02.2015

Haynes group undergraduates Nathan, Mike, and Kadir are all awarded Heisig-Gleysteen Fellowships to support their full-time summer research.

03.22-03.26.2015

Katie and Nathan present their research at the Spring 2015 National American Chemical Society meeting in Denver, CO.

03.20.2015

Collaborative work between MRSEC RET participant, Cassandra Knutson, Tony, and the Penn group is accepted for publication in J. Chem. Ed.. This paper focuses on updating a classic general chemistry laboratory with modern online tools and cameraphones.

03.06.2015

Congratulations to Joe on passing his oral preliminary exam!

03.03.2015

Joe's blog post is featured on the sustainable-nano.com website.

02.25.2015

Christy gives an invited talk at the "Nanomaterials for Energy" Gordon Research Conference.

01.27.2015

Solaire's work, focused on cytoskeletal imaging analysis of platelets, is accepted for publication in Analytical and Bioanalytical Chemistry.

12.19.2014

Mike McDermott, a sophomore undergraduate chemistry major, joins the Haynes group to work with Zhe on mesoporous silica nanomaterials.

12.16.2014

Autumn's blog post is featured on the sustainable-nano.com website.

12.12.2014

Matt Styles successfully defends his undergraduate honor's thesis based on work done in the Haynes lab, titled "Mimicking Native Receptors for the Detection of Ricin B-Chain via Surface-Enhanced Raman Spectroscopy on Gold Film-Over-Nanosphere Substrates".

12.02.2014

Collaborative work examining the effects of specific phospholipids on platelet secretion and adhesion, lead by Secil, Audrey, and Donghyuk, is accepted for publication in Analytical Chemistry.

11.20.2014

Two new graduate students join the Haynes Research Group - welcome Hyunho Kang and Bo Zhi!

11.18.2014

Sunipa's blog post is featured on the sustainable-nano.com website. This blog entry was picked up and featured on ScienceSeeker.

11.10.2014

Christy gives an invited talk at the Indian Institute of Technology (IIT) Madras in Chennai, India as part of the Royal Society of Chemistry "road show".

11.07.2014

Christy gives an invited talk at the University of Hyderabad in India as part of the Royal Society of Chemistry "road show".

11.04.2014

Christy gives an invited talk at the Indian Institute of Technology (IIT) Delhi in India as part of the Royal Society of Chemistry "road show".

News Archive

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Funding

The Haynes Research Group receives gracious financial support from the following agencies:

Sloan Foundation

Sloan Foundation logo

A 2010 Sloan Fellowship from the Alfred P. Sloan Foundation

Dreyfus Foundation

Dreyfus Foundation logo

A 2009 Camille Dreyfus Teacher-Scholar Award from the Dreyfus Foundation

National Institutes of Health

NIH New Innovator logo

A 2008 New Innovator Award from the National Institutes of Health

University of Minnesota

Univeristy of Minnesota logo

Start-up funds and a McKnight Land-Grant Professorship from the University of Minnesota

National Science Foundation

NSF logo

A National Science Foundation CAREER award

3M

3M logo

A 3M Non-Tenured Faculty Grant

Kinship Foundation

Searle logo

A Kinship Foundation Searle Scholar Award

American Chemical Society

ACS PRF logo

An American Chemical Society Petroleum Research Fund Grant

Center Collaborations

The Haynes Group is active members of these centers:

Center for Sustainable Nanotechnology logo Univeristy of Minnesota MRSEC logo