The Haynes group focuses on applications of analytical chemistry in the fields of immunology and toxicology, with much expertise in the area of single cell analysis.
One major area of interest is nanotoxicology - an emerging field investigating the biological and ecological impacts of engineered nanomaterials.
Another major focus in the group is on studying fundamental properties of cells involved in inflammation. In fact, the Haynes group has performed the first ever real-time single blood platelet measurements, examining the chemical messenger molecules that platelets secrete upon stimulation.
While most of the Haynes lab research employs electrochemical and spectroscopic techniques, the group is always exploring new and exciting technologies to answer pressing bioanalytical questions.
By tradition, our summer undergraduate research symposium was accompanied by our annual pie bake-off. This year's winning pie was an oreo chocolate peanut butter pie made by Joe. We'll be sad to have our summer visitors leave, but at least they'll leave with a sugar high.
We made our 11th annual visit to the W. 7th Community Center in St. Paul to do fun and inspiring chemistry activities with elementary and high school aged students. Peter and Hyunho coordinated this year's event, and the Haynes group was joined by members from the Feng, Carlson, and Frontiera groups.
Natalie led an outreach effort with the "Discover STEM" program to teach high school students about the chemistry of climate change.
Victoria and Hyunho present an invited lecture at 3M about their collaborative work on SERS detection of toxins.
Christy gives an invited talk about the group's work at the Blavatnik Science Symposium at the New York Academy of Sciences.
Christy wrote an editorial for Analytical Chemistry adapted from her recent sustainable-nano.com blog post.
Hyunho and Bo present their research results at the Department of Chemistry's annual "3rd year symposium".
Welome to two more summer students, Kyle and Sam, who will be summer researchers in the Haynes lab as part of the Lando Research Program and MRSEC REU Program, respectively. Kyle will be working with Amani while Sam will be working with Bo.
Congratulations to Sunipa for winning a poster award at the University of Minnesota iPrime meeting!
Congratulations to Summer 2016 REU student Susan Pham as well as Bo on the acceptance of collaborative work with the Feng, Fairbrother, Rosenzweig, and Hamers groups in the Journal of Chemical Education. This carbon dot laboratory activity for high school or college students was inspired by Susan's summer 2016 research project.
Welome to our first two summer students, Anaeli and Lizbeth, who will be summer researchers in the Haynes lab as part of the Center for Sustainable Nanotechnology's REU/REV program. Anaeli will be working with mentors Autumn and Peter while Lizbeth will be working with Natalie.
Congratulations to Hattie as well as former undergraduate researcher Nathan Klein on the acceptance of collaborative work with the Garwood group in Magnetic Resonance in Medicine. This manuscript explores the limits of detection using SWIFT-based MRI and iron oxide nanoparticles.
Congratulations to Kang on being chosen as a new trainee for the UMN Biotechnology Training Grant!
Congratulations to alumnus Adam Juelfs on the acceptance of collaborative work with the Pui group, focused on granular activated carbons for gas filtration, for publication in Carbon.
Congratulations to Amani and Hattie, as well as group alumni Katie and Adam, on the acceptance of collaborative work with the Pomerantz and Garwood groups, focused on perflurocarbon-filled mesoporous silica for fluorine-MRI-based oxygen sensing, for publication in ACS Nano.
Sunipa's blog post about nanotechnology in art conservation is featured on the Sustainable Nano blog.
Congratulations to alumni Audrey Meyer, Sarah Gruba, Donghyuk Kim, Ben Meyer, Secil Koseglu, and collaborator Joseph Dalluge on the publication of Haynes group work, focused on how lipid sterochemistry influences exocytosis, in Biochimica et Biophysica Acta - Biomembranes.
Undergraduate researcher Sam Bryson present his work at the Undergraduate Research Opportunities Program symposium.
Congratulations to undergraduate researchers, Kyle Johnson, Katie Landy, and Eileen McIntire, who have each won University of Minnesota scholarships based on their outstanding achievement in undergraduate research as well as overall scholastic excellence!
Christy gives an invited colloqium at the University of Rochester focused on work in the Center for Sustainable Nanotechnology.
Congratulations to undergraduate researchers, Kyle Johnson and Katie Landy, who have both been awarded University of Minnesota Heisig/Gleysteen fellowships to support their research in the Haynes group for Summer 2017!
Christy is featured on the "People Behind the Science" podcast, giving her an opportunity to highlight the Haynes research group, great collaborators, and the UMN Department of Chemistry.
Autumn, Bo, Kyle and Christy attend the Spring 2017 National ACS Meeting in San Francisco. Autumn gave an oral presentation while Bo and Kyle gave poster presentations, all on CSN work!
Christy Joins the University of Minnesota MRSEC Executive Committee.
Natalie wins a National Science Foundation Graduate Research Fellowship! Undergraduate group alumnus, Matt Styles, also wins one to support his graduate research at the University of Wisconsin.
Autumn wins a Mary Haga Travel Award from the Xi Chapter of Graduate Women in Science to support her travel to the Spring 2017 National ACS Meeting where she will be giving an invited oral presentation.
Christy gives and invited talk, focused on collaborative CSN work, at Pittcon 2017 in Chicago.
Congratulations to Zhe, Hattie, and Mike on the acceptance of their collaborative work with the Bischof, Garwood, and Brockbank groups, focused on nanoparticle-based rewarming of cryogenically preserved tissues, for publication in Science Translational Medicine.
Congratulations to alumni Xiaojie and Mollie and current group member Dr. Zhe Gao on the acceptance of their work, focused on microfluidic studies of neutrophil/endothelial cell interactions, for publication in BBA - General Subjects.
Congratulations to Amani on passing his oral preliminary exam!
Congratulations to Natalie on passing her oral preliminary exam!
Congratulations to Kang on passing her oral preliminary exam!
Collaborative work between the Haynes and Barocas groups, focused on mathematical modeling of the fusion pore during exocytosis, is accepted for publication in Integrative Biology.
Collaborative CSN work led by Ian and Mimi on the proactive redesign of nanoscale NMC battery materials is accepted for publication in ES:Nano.
Collaborative CSN work led by Autumn on a new assay to screen for nanoparticle toxicity to bacteria is accepted for publication in Analytical Chemistry.
Collaborative CSN work led by Autumn on how nanoparticle purification schemes impact nanoparticle toxicity is accepted for publication in Analytical Chemistry.
Christy gives an invited seminar at the University of Colorado, Denver.
Congratulations to undergraduate researchers Katie Landy and Sam Bryson for winning Undergraduate Research Opportunity Project (UROP) awards to continue their research with graduate mentors Joe and Victoria/Hyunho, respectively!
Congratulations to Natalie and Peter on the acceptance of their collaborative CSN research highlight, titled "Speciation and transformations of silver released from Ag NPs in three species," in the journal Environmental Science: Nano.
The Haynes group happily welcomes three new graduate students to the group: Peter Clement, Jiayi He, and Becky Rodriguez. You can learn more about them on our people page.
Bo's blog post about appreciating parallels between nano-art and the macro-scale natural world is featured on the Sustainable Nano blog.
Natalie's blog post about how nanoscale features on ivy let it climb brick walls is featured on the Sustainable Nano blog.
Autumn's collaborative work exploring the toxicity of nanoscale titania to S. oneidensis is accepted for publication in Chemosphere.
Christy is featured in The Analytical Scientist's annual "Power List".
Congratulations to alumna Audrey Meyer on the publication of her work in collaboration with the Arriaga group to do untargeted MS analysis of mast cell-secreted species.
Congratulations to Zhe on winning 1st place at the Institute for Engineering in Medicine postdoc poster session!
Congratulations to Sunipa on winning a FACSS student poster award at SciX 2016!
Congratulations to Victoria on winning a Journal of Physical Chemistry poster award at the Van Duyne symposium!
Haynes group alumnus, Dr. Audrey Meyer, accepts a new position as a Senior Process Engineer at Boston Scientific (back in the Twin Cities!). We wish her well in this new role!
Christy gives an invited seminar at the University of North Carolina, Charlotte.
A new semester is underway, and the Haynes group meeting schedule is now available. New first year graduate students are welcome to join us to learn more about the group.
Congratulations to Zhe on the acceptance of her collaborative work with the Hogan and Bischof groups, titled "Ion Mobility based Quantification of Surface Coating Dependent Binding of Serum Albumin to Superparamagnetic Iron Oxide Nanoparticles," in the journal ACS Applied Materials and Interfaces.
Congratulations to Ben, Sarah, and Audrey (all graduated!) on the acceptance of their collaborative work titled "Analysis of Neuropeptide-Induced Mast Cell Degranulation and Characterization of Signaling Modulation in Response To IgE Conditioning," in the journal ACS Chemical Biology.
Haynes group alumnus, Dr. Yu-Shen Lin, accepts a new position as Senior Research Chemist at Ferrotec Corporation in New Hampshire. We wish him well in his new role!
Christy attends the Fall 2016 National ACS Meeting in Philadelphia and gives 4 invited talks: one on work determining the role of lipopolysaccharides in regulating nanoparticle/bacteria interactions, one on biomedical applications of mesoporous silica-coated iron oxide nanoparticles, one on single cell platelet measurements, and one on toxicity assessment of nanoscale battery materials. It was an exhausting but exciting conference!
Congratulations to Katie on the acceptance of her collaborative work with the Hogan and Bischof groups, titled "Quantifying Intra- and Extracellular Aggregation of Iron Oxide Nanoparticles and its Influence on Specific Absorption Rate," in the journal Nanoscale.
Christy officially joins the the "Nanostructural Materials and Processes Program" within the University of Minnesota's IPrime program. This new affiliation will help promote collaboration between the Haynes research group and industrial scientists and engineers.
Christy and Joe attend the ICEENN meeting in Golden, CO where Christy delivers a keynote talk and Joe presents a poster. They also get to spend time with CSN collaborators Prof. Rebecca Klaper, Prof. Howard Fairbrother, Arielle Mensch, Emily Caudill, Liz Laudadio, Margy Roberts, and Jared Bozich.
Congratulations to Autumn and Natalie on the acceptance of their collaborative CSN research highlight, titled "Unveiling the mechanisms underlying nanoparticle-induced ROS generation and oxidative stress," in the journal Environmental Science: Nano.
Congratulations to Solaire, Autumn, and Kayeong on the acceptance of their perspective article "Super-Resolution Imaging for Monitoring Cyotskeleton Dynamics" in Analyst.
Haynes group alumnus, Dr. Secil Koseoglu, accepts a new position at Takeda Pharmaceuticals in Boston. We wish her well in this new role!
The group had our annual pie bake-off to complment our end-of-summer undergraduate symposium. Both the talks and the pie were fantastic!
Congratulations to Hattie for co-leading collaborative work with the Garwood and Bischof groups titled "Quantification and Biodistribution of Iron Oxide Nanoparticles in the Primary Clearance Organs of Mice using T1 Contrast for Heating" that was just accepted for publication in Magnetic Resonance in Medicine.
Xiaojie Wu successfully defends his PhD thesis entitled "Development of Biomimetic Microfluidic Platforms for Cellular Interaction Studies."
The Haynes group along with selected members of the Carlson, Frontiera, and Feng labs spend the afternoon at W. 7th Community Center doing demonstrations and hands-on activities with 70 children. This 11th annual event was organized by Natalie, and everyone had a great time.
Congratulations to Amani on being chosen as a trainee for the Chemical Biology Interface Training Grant.
Congratulations to Zhe for leading collaborative work on SERS sensing in core-shell nanoparticles; her paper was just accepted for publication in Analyst.
Congratulations to Natalie on being chosen as a trainee for the University of Minnesota Biotechnology Training Grant.
Welcome to Peter Clement, an incoming Chemistry graduate student, who will be spending the summer in the Haynes lab working with mentor Natalie Hudson-Smith.
Collaborative work led by Tony titled "Surface-Enhanced Raman Spectroscopy Detection of Ricin B Chain in Human Blood" is accepted for publication in Journal of Physical Chemistry C to be part of the "Richard P. Van Duyne Festschrift" special issue.
Welcome to Anna Krieger, a Department of Chemistry Lando REU, who will be spending the summer in the Haynes lab working with mentor Kang Xiong-Hang.
Victoria and Christy give invited talks while Zhe, Joe, and Sunipa present posters at IPrime 2016.
Welcome to Susan Pham, a Center for Sustainable Nanotechnology REU, who will be spending the summer in the Haynes lab working with mentor Bo Zhi.
Collaborative work led by Victoria titled "SERS Detection of Ricin B-Chain via N-Acetyl-Galactosamine Glycopolymers" is accepted for publication in ACS Sensors.
Christy gives an invited seminar at The Ohio State University.
Nathan Klein successfully defends his undergraduate honors thesis entitled "Analytical Studies of Inorganic Nanoparticle Applications: Imaging in Complex Biological Matrices and Heat-mediated Cargo Release."
Ian Gunsolus successfully defends his PhD thesis entitled "Engineered Nanomaterial Interactions with Bacterial Cells."
Kyle Johnson is chosen as a winner of the Thomas DuBruil Undergraduate Research Award for 2016. This award is made to a junior who has demonstrated outstanding achievement in undergraduate research in chemistry at the University of Minnesota.
Sarah Gruba successfully defends her PhD thesis entitled "Exploration of Platelet and Mast Cell Communication: A Study of Membrane Lipids, Asthma, and Inflammation."
Christy gives an invited seminar in the Chemistry Department at University of Arizona.
Undergraduate researcher Kyle Johnson has been awarded a Heisig-Gleysteen Fellowship to support full-time summer research in the Haynes lab- congratulations to Kyle!
Former undergraduate researcher Matt Styles, now in Helen Blackwell's research group at UW - Madison, is awarded an honorable mention in the 2016 National Science Foundation Graduate Research Fellowship competition.
Undergraduate researcher Nathan Klein is awarded a 2016 National Science Foundation Graduate Research Fellowship to support his future graduate work - congratulations to Nathan!
Collaborative work led by Katie titled "Predictable Heating and Positive MRI Contrast from a Mesoporous Silica-Coated Iron Oxide Nanoparticle" is accepted for publication in Molecular Pharmaceutics.
Christy gives an invited seminar titled "Leveraging Analytical Methods to Explore Platelet Biology" in the University of Minnesota Department of Integrative Biology and Physiology.
Ian, Christy, and collaborators are featured in local news segments on FOX9 and KARE11 discussing recent work on NMC interaction with bacteria. The work is also covered in the Minnesota Daily, Science Daily, Watts Up With That?, and Green Car Congress.
Hyunho passes his PhD candidacy exam - congratulations!
Solaire Finkenstaedt-Quinn successfully defends her PhD thesis entitled "A Study on the Regulation Mechanisms of Platelet Activation."
A manuscript describing work done jointly by Ian and CSN collaborator Mimi Hang, titled "Impact of Nanoscale Lithium Nickel Manganese Cobalt Oxide (NMC) on the Bacterium Shewanella oneidensis MR-1" is accepted for publication in Chemistry of Materials.
Bo passes his PhD candidacy exam - congratulations!
Undergraduate researcher, Eileen McIntire, joins the Haynes research group to work with mentor Sunipa Pramanik to assess the bacterial toxicity of silicon nanocrystals.
Christy joins the board of OXIDE, the "Open Chemical Collaborative in Diversity Equity".
A manuscript describing work done by Solaire and Sarah, titled "Variations in Fusion Pore Formation in Cholesterol-Treated Platelets" is accepted for publication in Biophysical Journal.
A manuscript describing work done by Tony in collaboration with the Penn lab, titled "Quantifying Gold Nanoparticle Concentration in a Dietary Supplement Using Smartphone Colorimetry and Google Applications" is accepted for publication in the Journal of Chemical Education.
Christy gives an invited talk at Pacifichem in Honolulu, Hawaii.
Christy is featured on the Analytical Chemistry podcast discussing the group's recent feature article about monitoring magnetic nanoparticles in biological matrices.
Christy's blog post is featured on the sustainable-nano.com website.
A review article written by Ian, titled "Analytical Aspects of Nanotoxicology," is accepted for publication in Analytical Chemistry.
Christy gives a talk at the 2015 Sustainable Nanotechnology Organization meeting in Portland, Oregon.
Kadir's blog post is featured on the sustainable-nano.com website.
Collaborative Center for Sustainable Nanotechnology work led by Dr. Vivian Feng is identified as one of the 25 most downloaded Chemical Science articles between July-September 2015.
Christy co-edits a joint "virtual issue" between Chemical Research in Toxiciology, ACS Nano, and Nano Lett on the topic of Nanoparticle Toxicology.
Autumn's blog post is featured on the sustainable-nano.com website.
Christy gives a talk at SciX 2015 in Providence, RI.
Congratulations to Dr. Hattie Ring for winning 1st place in the post doc division of the poster competition at the Instintute for Engineering in Medicine annual conference.
Dona-Carla Forester joins the group as a new undergraduate researcher - she will be working with Autumn doing nanotox research.
Longtime undergraduate researcher, Kadir, departs for a 3 month research exchange in Germany.
Christy gives an invited seminar at Hope College in Holland, MI.
A feature article written by Katie, Hattie, Hyunho, and Nathan, titled "Characterization of Magnetic Nanoparticles in Biological Matrices," is accepted for publication in Analytical Chemistry.
Collaborative work with the Massari lab exploring molecular confinement in mesoporous silica is accepted for publication in Journal of Physical Chemistry C.
The Center for Sustainable Nanotechnology is funded as a phase 2 "Center for Chemical Innovation." With this accomplishment, the collaborative team will have the opportunity to work together for the next 10 years. Christy has accepted the official position of Associate Director for the center.
The Haynes group makes their annual pilgrimage to the Minnesota State Fair.
Katie Hurley successfully defends her PhD thesis entitled "The Power of Rust and Sand at the Nanoscale: Iron Oxide and Mesoporous Silica Nanoparticles for Biomedical Applications."
The phase 1 women faculty of the Center for Sustainable Nanotechnology, including Christy, are recognized among the top 100 Inspiring Women in STEM by "Insight into Diversity" magazine.
Victoria, Solaire, and Christy attend and present the group's work at the ACS National Meeting in Boston, MA.
Autumn and Ian's collaborative work with the Klaper and Murphy groups throught the CSN is accepted for publication in ES:Nano.
Congratulations to Solaire on winning a travel award from the MN Section of the American Chemical Society! This award will support her attendance and presentation at the Boston ACS meeting in August 2015.
As Prof. Vivian Feng finishes her year sabbatical in the Haynes lab, she took the Haynes lab out for celebratory ice cream at Izzy's. We will miss seeing her everyday but look forward to continued collaboration.
Ian and Kadir's collaborative work with the Buhlmann group is accepted for publication in Science of the Total Environment.
The Haynes group went canoeing on Medicine Lake on this beatiful summer day.
Ian's work on the critical role of lipopolysaccharides in nanoparticle/bacteria interactions, done with collaborators in the Center for Sustainable Nanotechnology, is accepted for publication in Environmental Science & Technology.
An editorial on the topic of gender-based implicit bias that Christy co-wrote with Jonathan Sweedler is published in Analytical Chemistry.
Christy becomes the Department of Chemistry's vice chair.
Sarah Schoeller, a MRSEC RET, joins the Haynes group for a summer research experience.
Autumn, Ian, and Christy spend an intellectually stimulating week at the "Environmental Nanotechnology" GRC in Vermont.
An ACS SEED program high school student, Ka Lia Xiong, joins the Haynes group for the summer to work with Joe.
An incoming UMN graduate student, Amani Lee, joins the Haynes group for the summer to work on a collaborative project with the Pomerantz group.
Xiaojie and Molly's microfluidic study of neutrophil transendothelial migration is accepted for publication in Analyst.
Ian and Kadir's collaborative work with Maral in the Buhlmann lab is accepted for publication in Environmental Science & Technology.
Sara, Autumn, and Victoria all give talks at the UMN 3rd year graduate symposium.
Three undergraduates join the lab for the summer: Nathan (from Macalester, working with Autumn), Jake (from Tulane, working with Sunipa), and Emily (from Ripon, working with Xiaojie). More to come soon...
A massively collaborative Center for Sustainable Nanotechnology "outlook" on nanoparticle sustainability is accepted for publication in ACS Central Science.
Christy gives an invited seminar in 3M's "Tech Forum".
Christy is awarded the 2015 Sara Evans Faculty Woman Scholar/Leader Award sponsored by the University of Minnesota Office for Faulty and Academic Affairs and the Women’s Center.
Ben, Audrey, and Sarah's work on airway smooth muscle-related mast cell degranulation is accepted for publication in Biochimica et Biophysica Acta - General Subjects.
Katie's blog post is featured on the sustainable-nano.com website.
Nathan is chosen as our department's recipient of the 2015 David A. and Merece H. Johnson Scholarship for outstanding achievement in undergraduate research as well as overall scholastic excellence.
Undergraduate researcher Nathan Klein is featured in the Star Tribune.
Ian is chosen to receive a 2015-2016 University of Minnesota Doctoral Dissertation Fellowship.
Katie's blog post is featured on the sustainable-nano.com website.
Christy gives an invited talk at the ASME 4th Annual "Nanoengineering for Biology and Medicine" conference.
After being nominated by Haynes group graduate students, Christy is is chosen for the "2015 Advising and Mentoring Award" given by the UMN Graduate and Professional Student Assembly.
Sam, Katie, and Ashish's work on creating large pore volume silica nanoparticles is accepted for publication in Chemistry of Materials.
Christy gives an invited talk at the University of Minnesota "Design of Medical Devices" conference.
Sarah, Secil, Audrey, Ben, and Melissa's work on how platelets differ across species is accepted for publication in Biochimica et Biophysica Acta - Biomembranes.
Christy gives an invited seminar at Gustavus Adolphus College in St. Peter, MN.
Antonio Campos successfully defends his PhD thesis entitled "Surface-enhanced Raman Spectroscopy of Analytes in Blood".
Haynes group undergraduates Adam, Kyle, and Kadir are all awarded UROP funding to support their research.
Christy gives an invited seminar at the University of Pittsburgh.
Haynes group undergraduate Nathan Klein is awarded a prestigious Goldwater Fellowship.
Nathan, Katie, and Vivian's work developing dark field TEM as a technique to visualize nanoparticles within complex biological matrices is accepted for publication in Analytical Chemsistry.
Haynes group undergraduates Nathan, Mike, and Kadir are all awarded Heisig-Gleysteen Fellowships to support their full-time summer research.
Katie and Nathan present their research at the Spring 2015 National American Chemical Society meeting in Denver, CO.
Collaborative work between MRSEC RET participant, Cassandra Knutson, Tony, and the Penn group is accepted for publication in J. Chem. Ed.. This paper focuses on updating a classic general chemistry laboratory with modern online tools and cameraphones.
Congratulations to Joe on passing his oral preliminary exam!
Joe's blog post is featured on the sustainable-nano.com website.
Christy gives an invited talk at the "Nanomaterials for Energy" Gordon Research Conference.
Solaire's work, focused on cytoskeletal imaging analysis of platelets, is accepted for publication in Analytical and Bioanalytical Chemistry.
Mike McDermott, a sophomore undergraduate chemistry major, joins the Haynes group to work with Zhe on mesoporous silica nanomaterials.
Autumn's blog post is featured on the sustainable-nano.com website.
Matt Styles successfully defends his undergraduate honor's thesis based on work done in the Haynes lab, titled "Mimicking Native Receptors for the Detection of Ricin B-Chain via Surface-Enhanced Raman Spectroscopy on Gold Film-Over-Nanosphere Substrates".
Collaborative work examining the effects of specific phospholipids on platelet secretion and adhesion, lead by Secil, Audrey, and Donghyuk, is accepted for publication in Analytical Chemistry.
Two new graduate students join the Haynes Research Group - welcome Hyunho Kang and Bo Zhi!
Sunipa's blog post is featured on the sustainable-nano.com website. This blog entry was picked up and featured on ScienceSeeker.
Christy gives an invited talk at the Indian Institute of Technology (IIT) Madras in Chennai, India as part of the Royal Society of Chemistry "road show".
Christy gives an invited talk at the University of Hyderabad in India as part of the Royal Society of Chemistry "road show".
Christy gives an invited talk at the Indian Institute of Technology (IIT) Delhi in India as part of the Royal Society of Chemistry "road show".
A 2010 Sloan Fellowship from the Alfred P. Sloan Foundation
A 2009 Camille Dreyfus Teacher-Scholar Award from the Dreyfus Foundation
A 2008 New Innovator Award from the National Institutes of Health
Start-up funds and a McKnight Land-Grant Professorship from the University of Minnesota
A 3M Non-Tenured Faculty Grant
A Kinship Foundation Searle Scholar Award