Overview

Analytical Chemistry

Immunology

Toxicology


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The Haynes group focuses on applications of analytical chemistry in the fields of immunology and toxicology, with much expertise in the area of single cell analysis.

One major area of interest is nanotoxicology - an emerging field investigating the biological and ecological impacts of engineered nanomaterials.

Another major focus in the group is on studying fundamental properties of cells involved in inflammation. In fact, the Haynes group has performed the first ever real-time single blood platelet measurements, examining the chemical messenger molecules that platelets secrete upon stimulation.

While most of the Haynes lab research employs electrochemical and spectroscopic techniques, the group is always exploring new and exciting technologies to answer pressing bioanalytical questions.

News

03.20.2020

Collaborative CSN work including contributions from group undergraduate alumnus Kyle Johnson, on the role of wall teichoic acids in nanoparticle-bacteria association, is accepted for publication in Chemical Science.

03.13.2020

Congratulations to Becky on being awarded a 2020-20201 American Chemical Society Division of Analytical Chemistry Fellowship sponsored by Eli Lilly and Company!

03.12.2020

Collaborative CSN work including contributions from group alumnus Dr. Bo Zhi, on phototransformations of carbon dots, is accepted for publication in Environmental Science & Technology.

03.09.2020

Becky designed a cool new Haynes Lab logo - you can find it on our research page.

03.08.2020

Becky is featured in Chemical & Engineering News' Twitter campaign highlighting excellent women chemists.

03.04.2020

Hyunho's blog post about measuring nanoparticle size in suspension is featured on the Sustainable Nano blog.

02.28.2020

Amani is featured in UMN Chemistry's student voices series.

02.27.2020

Christy worked with Profs. George Schatz and Paul Weiss to assemble a virtual issue in honor of her PhD advisor, Prof. Richard Van Duyne. We highly suggest reading the editorial and the highlighted papers from Analytical Chemistry, Journal of Physical Chemistry, and ACS Nano.

02.24.2020

Congratulations to Clare on being chosen for Boston Scientific’s undergraduate summer internship program! We’ll miss Clare this summer but are excited for her!

02.19.2020

Congratulations to Meghan for winning a Mitacs-Fulbright Canada Globalink Award and Internship! Meghan will use this award to spend summer 2020 at the University of Montreal studying atmospheric chemistry with Dr. Patrick Hayes.

02.18.2020

Becky is featured in UMN Chemistry's student voices series.

02.10-14.2020

Christy gives an invited lecture and 12 hours of short course as part of the 40th Summer School on Chemistry at the Federal University of São Carlos, Brazil.

02.06.2020

Congratulations to Becky for winning a University of Minnesota Louise T. Dosdall Fellowship for the 2020-21 academic year!

02.04.2020

Collaborative CSN work led by Peter Clement and with contributions from Meghan and group alumni Joe and Autumn, on bacterial impact of multiphase lithium cobalt phosphate nanomaterials, is accepted for publication in Chemical Research in Toxicology.

01.27.2020

Becky is chosen as a recipient of the WCC Merck Research Award, recognizing her research excellence with an invited talk at a special award symposium at the national ACS meeting. Congratulations Becky!

01.24.2020

Christy gives an invited lecture about collaborative CSN work at the University of Florida.

01.22.2020

Christy gives an invited lecture about collaborative CSN work as the Dean Martin lecturer at the University of South Florida.

01.09.2020

Welcome to Mary McIntire, a new University of Minnesota undergraduate researcher who will be working with Xiaoxiao on carbon dot synthesis.

01.08.2020

Collaborative work with the Hogan and Pomerantz groups, including important contributions from Amani, is accepted for publication in Analytical Chemistry. This paper describes a new ion mobility mass spectrometry method to characterize nanoparticle populations.

01.07.2020

Congratulations to Tana O'Keefe for passing her PhD oral candidacy exam!

01.01.2020

Christy joins the editorial advisory board for ACS Nano.

12.21.2019

Collaborative CSN work led by Joe Buchman and with contributions from group alumni Peter and Bo, on exploring the transformation and impact of high Ni content lithium ion battery materials, is accepted for publication in ES: Nano.

12.19.2019

Congratulations to Hyunho Kang on the successful defense of his doctoral thesis, titled "Design of Silicon Dioxide Nanomaterials and Understanding their Colloidal Behaviors for Sensing and Biological Applications."

12.15.2019

Collaborative work led by Prof. Klaus Schmidt-Rohr's group with contributions from Bo, on NMR analysis of CSN carbon dots, is accepted for publication in the Magnetic Resonance in Chemistry.

12.01.2019

Collaborative work led by Prof. Calvin Sun's group with contributions from Bo and Hyunho, on how crystallization methods influence pharmaceutical delivery, is accepted for publication in the International Journal of Pharmaceutics.

11.18.2019

Congratulations to Meghan on being awarded an ACS Undergraduate Award in Analytical Chemistry to recognize her excellent research achievements! Meghan is also a featured undergraduate in the UMN Chemistry Department annual newsletter.

11.12.2019

The Haynes group happily welcomes Riley Lewis, Eleni Spanolios, and Beza Tuga as new first year graduate students in the group. You can find a few details about them on our "people" page.

11.11.2019

Collaborative CSN work led by Joe Buchman, on using chitosan-coated mesoporous silica for agricultural applications, is accepted for publication in ACS Sustainable Chemistry & Engineering.

11.07.2019

Christy spends the day at Merck headquarters and gives an invited seminar.

11.06.2019

Collaborative work led by former Haynes group postdoc, Dr. Zhe Gao, on the scalable synthesis of core-shell nanoparticles for nanowarming is accepted for publication in Advanced Science.

10.20.2019

Christy is named to Analytical Scientist's 2019 Power List.

10.13-10.16.2019

Hyunho and Christy attend SciX 2019 in Palm Springs, CA where Christy gives a plenary lecture on the group's polymer-enabled sensor work and Hyunho presents a poster on his CSN work. Group alumni Drs. Melissa Maurer-Jones and Tian Autumn Qiu also presented invited talks in a symposium honoring Christy.

10.09.2019

Hyunho gives an invited seminar at the Connecticut Agricultural Experimental Station in New Haven, CT as part of his week-long lab exchange with Dr. Jason White.

10.08.2019

CSN work led by the Carlson group, with Haynes group contributions, is featured in the Star Tribune newspaper.

10.03.2019

Haynes group work on ITC-evaluation of polymer affinity agents is featured in the Spectroscopy magazine.

09.27.2019

Christy gives an invited lecture about carbon dots at the Oesper Symposium at the University of Cincinnati in honor of Prof. R. Mark Wightman.

09.23.2019

Congratulations to Amani on being recognized as the best graduate student poster presenter at the annual meeting for the Institute for Engineering in Medicine!

09.20.2019

Joe's blog post about designing nanoparticles for sustainability is featured on the Sustainable Nano blog.

09.16.2019

Congratulations to Hyunho on the acceptance of a manuscript exploring the driving factors for small molecule SERS detection using core-shell substrates in the Journal of Physical Chemistry C.

09.03.2019

Christy is a co-author on a new manuscript accepted in ACS Nano, written by a large group of leaders in SERS, titled "Present and Future of Surface Enhanced Raman Scattering."

08.29.2019

Congratulations to Natalie and Meghan, contributors on a collaborative CSN paper led by the Carlson group, on the acceptance of the paper titled "Chronic Exposure to Complex Metal Oxide Nanoparticles Elicits Rapid Resistance in Shewanella oneidensis MR-1," in Chemical Science.

08.26-29.2019

Christy shared Haynes group and CSN research on carbon dots during an invited talk at the National ACS Meeting in San Diego, CA.

08.16.2019

Congratulations to Bo Zhi on the successful defense of his doctoral thesis, titled "Group IV Element-based Luminescent Nanoparticles: Synthesis, Environmental Impact Evaluation, and Bio-imaging Applications." Shortly, Bo will be departing for a position as a senior research scientist at Zeon in Japan.

08.02.2019

Congratulations to Joe and Becky on the acceptance of a collaborative CSN paper titled "Coating Iron Oxide Nanoparticles with Mesoporous Silica Reduces their Interaction and Impact on S. oneidensis MR-1," in Chemosphere.

08.01.2019

Congratulations to Becky on being chosen for a 2019-2020 Excellence Fellowship! This competitive fellowship recognizes Becky's outstanding research and leadership in the UMN Chemistry Department.

07.27.2019

Congratulations to Amani on being chosen as a 2019 Institute for Engineering in Medicine (IEM) Doctoral Fellow! This award will support Amani's final year of doctoral work and allow him to be an ambassador for the IEM.

07.19.2019

A collaborative MRSEC paper titled "Bacterial Toxicity of Germanium Nanocrystals Induced by Doping with Boron and Phosphorous," including contributions from Bo and Natalie, has been accepted for publication in ACS Applied Nano Materials.

06.11.2019

Congratulations to Becky, group alumna Victoria, former undergraduate Sam Bryson, and collaborators in the Reineke and Schatz groups on the acceptance of a manuscript detailing design of polymer affinity agents for the detection of aflatoxin B1 in Molecular Systems Design & Engineering.

06.06.2019

Christy gives an invited lecture at Instituto de Tecnología Química in Valencia, Spain.

06.03.2019

Welcome to Emma Henshaw, a CSN summer undergraduate researcher from St. Lawrence University, who will be spending the summer in the Haynes lab working with mentor Hyunho Kang.

05.24.2019

Congratulations to Natalie, Meghan, group alumnus Nathan Klein, and CSN collaborator Miriam Krause on the acceptance of a manuscript detailing a model TEM for classroom/outreach use in the Journal of Chemical Education.

05.23.2019

Collaborative CSN work including contributions from Natalie, describing a microreactor for synthesizing metal oxide nanoparticles, is accepted for publication in Journal of Vaccum Science and Technology A.

05.21.2019

Congratulations to Hyunho and Davis on the acceptance of a manuscript demonstrating how to synthesize silica with a stable, positive zeta potential in Langmuir.

05.20.2019

Congratulations to Joe, Natalie, and Katie on the acceptance of a critical review focused on nanoparticle redesign for sustainability in Accounts of Chemical Research.

05.16.2019

Christy gives an invited lecture at Institut de Biologie Physico-Chimique in Paris, France as part of the CECAM workshop on "Biomolecular mechanisms at functionalized solid surfaces".

05.15.2019

Congratulations to Becky on winning the 2019 Richard D. Amelar and Arthur S. Lodge Fellowship for Outstanding Collaborative Research in Materials!

05.13.2019

The Haynes lab wins the University of Minnesota Chemistry Department's Safest Lab Award for Spring 2019.

05.01.2019

Collaborative CSN work including contributions from Bo, on functionalization of carbon-based nanoparticles, is accepted for publication in JACS.

04.08.2019

Congratulations to Meghan and Elaine, current undergradauate researchers in the Haynes lab, for having been chosen as recipients for the 2019 Lloyd W. Goerke Scholarship and the 2019 Robert C. Brasted Fellowship, respectively. These Chemistry Department awards recognize their excellence both in the classroom and in the laboratory!

04.05.2019

Both Meghan and Elaine, current undergradauate researchers in the Haynes lab, have been awarded Heisig-Gleysteen summer undergraduate research fellowships. This means that they'll be doing research full-time for summer 2019!

04.05.2019

Christy gives an invited lecture at Universitat Rovira i Virgili in Tarragona, Spain.

04.01-04.2019

Natalie presents two talks at the Spring 2019 National American Chemical Society meeting in Orlando.

04.02.2019

Becky is recognized with an Honorable Mention for the ACS Division of Analytical Chemistry Graduate Fellowship.

03.25-29.2019

Christy gives invited lectures at the University of Bath, Swansea University, and NUI Galway during her Royal Society of Chemistry award tour.

03.17-21.2019

Becky and Jiayi present their research at PittCon 2019 in Philadelphia.

03.09.2019

Christy is named a Distinguished McKnight University Professor.

03.01.2019

Congratulations to Natalie on a MN ACS Travel Award to support her upcoming presentations at the Spring 2019 National ACS Meeting in Orlando, Florida.

02.26.2019

Christy was interviewed for the Analytical Scientist.

02.10.2019

Congratulations to Natalie on winning a University of Minnesota 2019 Thesis Research Travel Grant! This grant will help support Natalie's month-long visit to Spain to complement Christy's sabbatical work.

02.07.2019

Congratulations to Kang, Kaila, and Anna on the acceptance of our first manuscript about platelets in malaria in ACS Infectious Diseases.

02.07.2019

Welcome to Clare Froehlich, a University of Minnesota Chemistry major who will be performing research in the Haynes lab working with mentors Becky Rodriguez and Jiayi He.

01.31.2019

Christy's blog post about art and sustainability in Morocco is featured on the Sustainable Nano blog.

12.20.2018

Congratulations to Dr. Sunipa Pramanik on the successful defense of her doctoral thesis, titled "Interactions of Semiconductor Nanoparticles with Environmentally Relevant Bacteria Model."

12.19.2018

Congratulations to Xiaoxiao on successfully completing her oral preliminary exam!

12.18.2018

Congratulations to Dr. Joe Buchman on the successful defense of his doctoral thesis, titled "An Investigation of Nanoparticle Toxicity Mechanisms against Environmentally Relevant Bacteria and the Potential for Sustainable Agriculture Applications."

11.19.2018

Bo's blog post about colorful carbon dots is featured on the Sustainable Nano blog.

11.12.2018

A new graduate student, Tana O'Keefe, joins the Haynes group to pursue her PhD in the area of sustainable nanotechnology. Welcome Tana!

10.31.2018

Collaborative work by Hyunho with the Frontiera group, on how silica impacts plasmonic heating, is accepted for publication in ACS Applied Materials & Interfaces.

10.22.2018

Collaborative work led by Victoria with the Reineke and Schatz groups, including contributions from Becky and undergraduate Sam Bryson, on using isothermal titration calorimetry to assess SERS affinity agents, is accepted for publication in Analytical Chemistry.

10.15.2018

Collaborative CSN work led by Autumn and including contributions from Peter, with a future-looking perspective on nanoparticle sustainability, is accepted for publication in ChemComm.

10.11.2018

Christy gave two invited talks at Humboldt University in Berlin, Germany.

09.24.2018

Both Bo and Zhe win 1st place for their posters at the Institute for Engineering in Medicine conference, Bo in the graduate student category and Zhe in the postdoctoral scholar category.

09.17.2018

Collaborative work led by Hyunho and including contributions from Joe, Becky, Hattie, Jiayi, and group alumna Dr. Kyle Bantz, on strategies for stabilizing nobel metal nanoparticles, is accepted for publication in Chemical Reviews. This manuscript will be featured in a themed issues on "Chemical Sensors."

09.13.2018

Collaborative CSN work including contributions from Natalie, on copper nanoparticles for agricultural applications, is accepted for publication in ACS Sustainable Chemistry and Engineering.

09.05.2018

Collaborative CSN work including contributions from Joe, on nanoparticle interactions with lipid bilayers, is accepted for publication in Langmuir.

08.22.2018

Collaborative work led by Victoria and including contributions from Becky, Natalie, Hyunho, Jiayi, and the Reineke group, on the design of SERS sensors, is accepted for publication in ACS Applied Materials & Interfaces.

08.20.2018

Collaborative MRSEC work led by Bo and including contributions from Natalie, on the toxicity of doped silicon nanocrystals, is accepted for publication in ACS Applied Nano Materials.

08.10.2018

Collaborative CSN work including contributions by Sunipa, Bo, Natalie, and Eileen, on the toxicity of core-shell quantum dots, is accepted for publication in ACS Applied Nano Materials.

08.08.2018

The Haynes group makes their annual trip to W. 7th Community Center to host hands-on activities for 80 excited kids. Special thanks to Peter for coordinating this year's visit!

08.07.2018

Collaborative CSN work including contributions from group alumni Autumn, Ian, and Katie, on the formation of lipid coronas on membrane-interacting nanoparticles, is accepted for publication in Chem.

08.07.2018

Joe's work "Using an environmentally-relevant panel of Gram-negative bacteria to assess the toxicity of polyallylamine hydrochloride-wrapped gold nanoparticles" is being featured in ES:Nano promotional materials.

08.01, 08/07.2018

Natalie and Meghan run a chemical education activity they've designed to teach about transmission electron microscopy with two groups of high school students visiting UMN as part of the DiscoverSTEM program.

07.16.2018

Work led by Hattie, on the use of the ferrozine assay to quantify iron in core-shell nanoparticles, is posted on ChemRxiv.

07.14.2018

Collaborative CSN work led by the Klaper lab, including contributions from Joe, on the toxicity of nanodiamond in Daphnia magna is accepted for publication in Environmental Research.

07.03.2018

Collaborative MRSEC work led by Sunipa, including contributions by Bo, Natalie, and Amani as well as undergraduate researchers Jacob and Eileen, on the toxicity of Si nanocrystals is accepted for publication in Environmental Science:Nano.

06.12.2018

Kang has been awarded a second year of funding with a National Institute of General Medical Sciences (NIGMS) Training Grant in Biotechnology.

06.08.2018

Collaborative CSN work co-led by Bo and Yi (at PNNL) on super-resolution imaging with carbon dots is accepted for publication in ACS Nano.

06.01.2018

Collaborative CSN work including contributions by Joe, Autumn, Bo, and Katie on the degradation and toxicity of nanoparticle/polymer composites is accepted for publication in Environmental Science:Nano.

06.01.2018

Natalie, Amani, and Kang all present their research at the UMN Chemistry Graduate Research Symposium.

05.30.2018

Christy is chosen as a finalist for the Blavatnik Award for Young Scientists. She is one of 10 chemists recognized with this honor.

05.29-05.30.2018

Joe, Amani, and Sunipa give oral presentations and Peter and Bo gave poster presentations about their research at the IPRIME meeting, sharing Haynes Lab work with industrial scientists.

05.15.2018

Jiayi passes her doctoral candidacy exam!

05.11.2018

Becky passes her doctoral candidacy exam!

05.08.2018

Christy is chosen as the Royal Society of Chemistry's 2018 Theophilus Redwood Award winner, recognizing her accomplishments in both analytical chemistry and scientific communication.

05.07.2018

Congratulations to undergraduate Kaila Kemnetz-Ness on being granted an "Undergraduate Research Opportunities Program" award to support her continued research in the Haynes group.

04.25.2018

Kyle successfully defends his undergraduate honors thesis!

04.24.2018

Christy has been chosen as the Coblentz Society's 2018 Craver Award winner. This award recognizes significant contributions in applied analytical vibrational spectroscopy.

04.23.2018

The University of Minnesota Joint Safety Team has recognized the Haynes Lab with the "Safest Lab Award" for Spring 2018.

04.21.2018

Christy delivers the plenary lecture at the Winchell Undergraduate Research Symposium in St. Paul, MN.

04.19.2018

Congratulations to undergraduate Meghan Cahill on being granted an "Undergraduate Research Opportunities Program" award to support her continued research in the Haynes group.

04.11.2018

Collaborative CSN and MRSEC work co-led by Natalie and Solaire, on educational activities to teach about the chemistry of climate change, is accepted for publication in the Journal of Chemical Education.

04.10.2018

Collaborative work on nanotheranostics, with contributions by Zhe, is accepted for publication in ACS Applied Materials & Interfaces.

04.03.2018

Congratulations to former summer researcher Susan Pham on winning a 2018 National Science Foundation Graduate Research Fellowship and to Peter Clement for being recognized with an Honorable Mention!

04.03.2018

Christy delivers the "Bryant Minor Lecture" in the Chemistry Department at the University of Utah.

04.02.2018

Collaborative CSN work co-led by Natalie, and with significant contributions by Peter, on how complex oxide nanoparticle morphology and crystal structure impact toxicity is accepted for publication in ACS Applied Nanomaterials.

03.30.2018

Congratulations to Meghan, an undergraduate researcher co-mentored by Natalie and Peter, on being chosen as a winner of the Thomas DuBruil Undergraduate Research Award for 2018!

03.27.2018

Autumn successfully defends her PhD thesis, titled "Bacterial Response to Nanoparticles at the Molecular Level"!

03.22.2018

Elaine Kappel, a University of Minnesota undergraduate chemistry major, joins the Haynes group to work with Hattie on developing assays to characterize nanoparticles.

03.21.2018

Collaborative work that includes contributions from Bo and Autumn, as part of the CSN, on amine-terminated Au nanoparticles is accepted for publication in Langmuir.

03.20.2018

Congratulations to Amani on winning the Academic-Leadership Collegiate Scholarship, granted by the State of Iowa Black Belt Association (SIBBA) - this award recognizes Amani's leadership and academic merit!

03.18-03.22.2018

Natalie, Joe, Katie, and Christy attend and present research results at the Spring 2018 National ACS Meeting in New Orleans.

03.12.2018

Christy delivers an invited talk in the Chemistry Department at Rice University.

03.06.2018

Christy delivers an invited talk at the "OneChemistry Symposium" at Johns Hopkins University.

03.05.2018

Joe, Natalie, Bo, Hyunho, and Peter present their work a the Center for Sustainable Nanotechnology All-Hands meeting in Baltimore, MD.

02.28.2018

Congratulations to Joe on winning a travel grant from the MN section of the American Chemical Society to support his upcoming Spring 2018 ACS presentation in New Orleans, LA.

02.28.2018

Congratulations to Eileen on being chosen for an internship at Ecolab for Summer 2018.

02.21.2018

Christy gives an invited seminar in the Chemistry Department at Indiana University-Purdue University Indianapolis (IUPUI).

02.16.2018

Victoria successfully defends her PhD thesis, titled "Linear Polymer Affinity Agents for the Intrinsic SERS Detection of Food Safety Targets"!

02.08.2018

Christy co-guest edited a virtual issue of Analytical Chemistry highlighting selected women analytical chemists, including an editorial recognizing some challenges for women chemists.

01.22.2018

Katie Landy is chosen as a recipient of an I. M. Kolthoff award from the ACS Division of Analytical Chemistry based on her fantastic undergraduate research. Katie will be recognized with this award at the Spring 2018 National ACS meeting in New Orleans.

01.19.2018

Welcome to Sang-Hyuk Lee, a University of Minnesota Chemistry major who will be performing research in the Haynes lab working with mentor Amani Lee.

01.19.2018

Christy gives an invited seminar in the Chemistry Department at the University of Minnesota, Duluth.

01.18.2018

Peter passes his doctoral candidacy exam!

News Archive

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Funding

The Haynes Research Group receives gracious financial support from the following agencies:

Sloan Foundation

Sloan Foundation logo

A 2010 Sloan Fellowship from the Alfred P. Sloan Foundation

Dreyfus Foundation

Dreyfus Foundation logo

A 2009 Camille Dreyfus Teacher-Scholar Award from the Dreyfus Foundation

National Institutes of Health

NIH New Innovator logo

A 2008 New Innovator Award from the National Institutes of Health

University of Minnesota

Univeristy of Minnesota logo

Start-up funds and a McKnight Land-Grant Professorship from the University of Minnesota

National Science Foundation

NSF logo

A National Science Foundation CAREER award

3M

3M logo

A 3M Non-Tenured Faculty Grant

Kinship Foundation

Searle logo

A Kinship Foundation Searle Scholar Award

American Chemical Society

ACS PRF logo

An American Chemical Society Petroleum Research Fund Grant

Center Collaborations

The Haynes Group is active members of these centers:

Center for Sustainable Nanotechnology logo Univeristy of Minnesota MRSEC logo