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First-year graduate students Gabriella "Brie" Perell and Andrew Urick
received Grants-in-Aid of Research Program awards from Sigma Xi, a
scientific research society. Both are advised by Professor Will Pomerantz.
Brie is working on a general
protein-protein interaction strategy using alpha-helical mimetics. Her
first target is the CREB: KIX protein-protein interaction, a known
transcription factor protein interaction associated with acute myeloid
leukemia. She received $400 for expenses associated with her research.
Andrew is working on developing a 19F NMR screening assay as a hypersensitive technique for uncovering protein-ligand binding interactions. Currently, he is focusing on Brd4, a bromodomain containing protein that is overexpressed in several cancers. He received $942 toward expenses associated with this research.
The Sigma Xi Grant-in-Aid of Research Program has a highly competitive application process and only approximately 20 percent of applicants receive any level of funding.